Although asthma is a multifactorial condition the strongest risk factor in the etiology of asthma is atopy allergies atopic dermatitis allergic rhinitis an atopic individual has a significantly greater probability of developing asthma and persons with a family history of atopic disease are at greatest risk. Section 2 definition pathophysiology and pathogenesis of asthma and natural history of asthma 14 august 28 2007 as a guide to describing asthma and identifying treatment directions a working definition of asthma put forth in the previous guidelines remains valid asthma is a chronic inflammatory. Asthma is a chronic lung disease that inflames and narrows the airways it has no known cure but by identifying triggers and developing a proper management plan asthmatics can lead a healthy active life asthma affects people of all ages but it most often starts during childhood what causes asthma asthma has a strong genetic component
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